Casting the spell imbue champion causes a crash to desktop almost every time I try it. It does seem to be an intermittent problem however. I have got it to work on Janus early in the game, but trying to cast it on other champions later in the game always causes a crash (especial female ones, might be unrelated but thought I'd mention the trend).
Running a dual core AMD Athlon setup with Radeon HD5850 on WinXP32. DX diagnostic and savegame on request.