I skipped CIV V after loving CIV IV to death, so I am on the fence here
I did the same initially. I finally picked up CiV and G&K when steam had them 90% off or something equally hard to pass up, and I have to say, I quite enjoy it. Is it better than IV? That's really up to each individual, but it is good. BNW just made it better I think, though I don't have nearly as much time on BNW as I do on G&K. It's been my fall back game when I just can't quite seem to find anything else that motivates me
So, I would imagine that this being built off of a CiV type engine, if not the same one (I didn't read the interview or anything else) shouldn't be that problematic. Though I will keep on with my rule of never buying at release.
Lately I've been looking at Pandora quite a bit, but from the lets plays I've seen it just feels as though there is something missing from that game, I hope this one addresses that issue.