I've noticed while placing city plots that the mouse gets really goofy. Oftentimes actually creating the new construction in a square different (but nearby) the one I was intending to build into.
Similarly, while I try to select multiple units from a city stack to move out, if I hold down Shift while I move the mouse, it moves REALLY slow and jitters by about 1/4 inch. If I move my pointer over the unit, press shift and click, then release shift and repeat for all units I wish to select there is no such problem.
Ultimately, neither of these are game-breaking but it would certainly help smooth out the interface.
Thank you Stardock for taking the time and effort before, during, and most importantly after release to make sure that your games are solid over the long run.