The first time I loaded the game, I had that crash.  Then I went and updated my video card drivers.  The second time I loaded the game, I had that crash again.  After that, I have been able to play the game with no crashes...  So, not a lot of help here, but do make sure that you have the most updated video drivers.

 Honestly, I would be happy if I could go through a single hour without loading an autosave due to crashes. Constant crashing is the mean reason I don't play more.

I found in my experience, that may very well be your problem -- autosaves.  Try disabling them.  My game doesn't crash anywhere near as much as it used to after disabling this.  Fortunately for me, I prefer saving manually anyway.

That said, since there are still so many people who have trouble running this game smoothly (especially those who have updated drivers AND solid rigs), I think it would be a *wonderful* idea to have a section of this site (perhaps just one big thread pinned at the top of the support forum) dedicated to listing the most common crashes, what the reasons could be for causing them, and how to potentially fix them.  Because I wouldn't be surprised if there are only a small number significant reasons this is only affecting some people, while others have little to no problems.  As an additional bonus, the other side doesn't have to repeatedly ask to give PC specs, dx dialogs etc.  Meanwhile it's all up there for easy reference.

Sounds like a win-win to me.  Just something to consider.

Well, I don't know how much this will help you either (maybe it will), but have you tried disabling the screensaver?  Aside from disabling auto-saves, I also found doing ANY sort of switching focus from this game will drastically raise the odds of inevitable crashing.  Using screensavers, alt-tabbing, anti-virus pop-up messages, etc.  Unless you've already tried all this, please do.  I suppose it depends how badly you want it to work.

I admit it's a pain to have to jump through all these hoops just to make this overly-sensitive game run smoothly (and I don't think you should have to with a decent rig like yours either).  My situation is really just a much less severe version of yours; I don't crash nearly as often anymore, but still occasionally -- which is more often than any other game I play.  It's been that way for me since Elemental WoM, as well as FE.  These 3 are the *only* games I've ever had any trouble running smoothly in recent years -- the same 3 games that oddly have the lowest spec requirements when compared to other new games I've installed, all run smoothly without a hitch.

So please, Stardock.  A pinned thread or 'help page' dedicated to known crashes (ones that can't be fixed in a patch), where people can do their own troubleshooting.  List any common reasons/causes for crashes.  Tell us any crashes that you (the devs) have had yourselves, or others we've reported to you, and list solutions that you know have worked.

Please don't get me wrong: LH is a fantastic game -- it's hard to believe much better it became in just a few years.  But sadly, it's apparent that enough people are still having problems to warrant something like this.

As a user who's waiting to get a fixed game  - I'm really interested in seeing fixes come out for the numerous crashes which are being reported on a 'semi-regular' basis (yes - I've posted one of them). 

I expect that LH is very complex (due to it's design approach) and no doubt whilst many of us might be experiencing CTD's I imagine that the causes are numerous and varied. I've accepted that these things can take time to fix and I trust that Stardock (given their commitment to users) will get around to fixing them. However what I'd really like to see is some communication/feedback and a plan to fix them.

I'd encourage all the folk who are still experiencing these to continue talking about the problems as sometimes its the conversation & online interactions which throw up possible answers - particularly if the technical guys are running out of options and can't root cause the problems.