Try setting the resolution to match your desktop in the prefs.ini file (it can be found in My Documents\My Games\Elemental).
No luck. Also no change with any of the following:
-Changing to a single monitor desktop
-Deleting the prefs file/resetting it to default values
-Changing to windowed mode in the prefs file.
They all result in the same app crash pointing to elemental.exe and user32.dll This problem is present in Beta-A, B, and C
