Quite often when I load a saved game, it either freezes directly after I hit the load button, or when generating the world. I end up bring up the task manager to kill the process. Unfortunately, it did not seem to create a debug.err or anything of the like. This has happened on two different saves so far, and both times I've had to load up an older auto-save instead. Would be pretty annoying if it wasn't still in Beta. 
I'm guessing the save file is getting corrupt somehow? I'd attach the save file, but I don't want to download dropbox and set up an account and whatever. (I'm lazy). If someone wants it I can email it though.
Anyway, I'm running on a:
AMD Athlon 64 X2 Dual core 5600+ 2.81 Ghz
4 Gigs of memory
Windows 7 Home Premium
NVidia Geforce GTX 275
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On a semi unrelated note, the title screen and the intro lag like crazy for me as well, but in game things are fine. No clue why!