Re-mapping shortcut keys?

Can anyone tell me how to re-map the shortcut keys?  I use a non-QWERTY layout on a non-standard keyboard, and many of the default keyboard shortcuts are very inconvenient.  I'm fine with editing .ini or .xml files if I need to, but I haven't found where the keymap is defined.  Anyone else figure this out?  (Also, every game should enable re-mapping of keys in an in-game options menu.  It's an easy feature to implement, and improves accessibility. /rant)