Reply #1 Top

Although this sounds un-related, please try a lower screen resolution in the Video tab of the options screen.  Does this enable the Save button?

 

Reply #2 Top

User posted followup: resolved by reinstall.

Reply #3 Top

Quoting kryo, reply 2
User posted followup: resolved by reinstall.
End of kryo's quote
The Critter and I (mostly, it was the Critter) discovered that deleting the prefs.ini will also fix the issue.  I imgaine he's trying to narrow down what specifically is the cause.