I love, by the way, the interactive feel of this support thread. It really feels the devs care about my problem; what with the quick replies and all.
At the moment, there's not much we can do in the forums to address OOM issues, beyond prompting for data if it's not provided. It's something that will probably be improved through successive updates.
The large address header patch will improve your longevity if you're on a 64bit system, as the game itself is only 32bit and cannot address more than 2GB under normal circumstances, though we can't support it as it may cause other side effects.