First attempt today was running it as usual with the new patch, it has crashed to desktop as usual. (I don't have the files for that, unfortunately.)
The second try was in windowed mode. I have a single monitor, so the issue you describe probably isn't having any effects, but I tried it anyway. Still got a CTD.
debug.err: http://dl.dropbox.com/u/5070559/debug%2004-22-2010%20try%201.err
Dump file: http://dl.dropbox.com/u/5070559/Elemental0_302-2010-04-23T00-05-21-718.zip
I than tried deleting the screen and than verifying, and also tried to start again in windowed mode, this also resulted in a CTD after the "Press space bar or enter" screen.
debug.err: http://dl.dropbox.com/u/5070559/debug%2004-22-3010%20try%202.err
Dump File: http://dl.dropbox.com/u/5070559/Elemental0_302-2010-04-23T00-16-43-187.zip
I am not actually sure what the video setting all mean, but will try lowering them to see if it effects this bug. Is there a list somewhere of what these settings are, and if not, is lower generally better, apart from the 1/0 ones? (My computer knowledge is lacking when it comes to a lot of this sort of stuff, as well as in what may be causing this particular problem.)